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SLC25A42

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GENERAL INFORMATION

Gene name

 SLC25A42

Gene description

 Solute carrier family 25, member 42

Protein class

 Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the mitochondria.

RNA cell category

 Mixed

Protein evidence

 Evidence at protein level

Main location

 Localized to the Mitochondria (supported)

Single-cell variation

 Single-cell variation in protein expression observed.

Mouse

 Localized to the Mitochondria in mouse cells.

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA049449
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ASSAYS
RNA expression
Human cells
Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the mitochondria.

Main location

 Mitochondria (supported)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA049449 Hep G2 Mitochondria
HPA049449 U-2 OS Mitochondria Intensity

MOUSE CELLS

Main location

 Mitochondria

Mouse gene

 ENSMUSG00000002346 (version 83)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location
HPA049449 NIH 3T3 Mitochondria

GENE INFORMATION

Gene name

 SLC25A42 (HGNC Symbol)

Synonyms

 MGC26694

Description

 Solute carrier family 25, member 42 (HGNC Symbol)

Entrez gene summary

 This gene encodes a solute carrier family 25 protein. Solute carrier family 25 proteins are localized to mitochondria and play critical roles in the transport of molecules across the inner mitochondrial membrane. The encoded protein is a mitochondrial transporter for coenzyme A (CoA) and adenosine 3',5'-diphosphate. [provided by RefSeq, Feb 2012]

Chromosome

 19

Cytoband

 p13.11

Chromosome location (bp)

 19063999 - 19112888

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000181035 (version 83.38)

Entrez gene

 284439

UniProt

 Q86VD7 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q86VD7

Antibodypedia

 SLC25A42 antibodies

PROTEIN BROWSER
SLC25A42-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC25A42-001
ENSP00000326693
ENST00000318596
Q86VD7 [Direct mapping]
Mitochondrial coenzyme A transporter SLC25A42
A0A024R7K2 [Target identity:100%; Query identity:100%]
Uncharacterized protein
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Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005347 [ATP transmembrane transporter activity]
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0015217 [ADP transmembrane transporter activity]
GO:0015228 [coenzyme A transmembrane transporter activity]
GO:0015866 [ADP transport]
GO:0015867 [ATP transport]
GO:0016021 [integral component of membrane]
GO:0035349 [coenzyme A transmembrane transport]
GO:0043262 [adenosine-diphosphatase activity]
GO:0080121 [AMP transport]
GO:0080122 [AMP transmembrane transporter activity]
Show all
 318 aa
35.4 kDa 		No 3

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.