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Most malignant tissues showed weak to moderate cytoplasmic and nuclear staining. Strongest staining was seen in colorectal carcinomas. Most malignancies showed several negative cases.
Several malignancies showed weak to moderate nuclear immunoreactivity. Hepatocellular carcinomas displayed strong cytoplasmic staining while a majority of testicular cancers showed strong nuclear positivity. Lung, gastric and endometrial cancers were in general weakly stained or negative.
Q8N680 [Direct mapping] Zinc finger and BTB domain-containing protein 2
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Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)