Cell atlas - ZBTB2 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ZBTB2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	ZBTB2
Gene description	Zinc finger and BTB domain containing 2
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol & nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported), Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA023458 , HPA023487
	SHOW MORE

ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol & nucleoplasm.

Main location

Nucleoplasm (supported), Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA023458	A-431	Nucleoplasm
HPA023458	U-2 OS	Nucleoplasm
HPA023458	U-251 MG	Nucleoplasm
HPA023487	A-431	Nucleoplasm
HPA023487	A-431	Cytosol
HPA023487	U-2 OS	Nucleoplasm
HPA023487	U-2 OS	Cytosol
HPA023487	U-251 MG	Nucleoplasm
HPA023487	U-251 MG	Cytosol

GENE INFORMATION
Gene name	ZBTB2 (HGNC Symbol)
Synonyms	bA351K16.2, KIAA1483, ZNF437
Description	Zinc finger and BTB domain containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q25.1
Chromosome location (bp)	151364117 - 151391548
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000181472 (version 83.38)
Entrez gene	57621
UniProt	Q8N680 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N680
Antibodypedia	ZBTB2 antibodies

PROTEIN BROWSER

ZBTB2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZBTB2-001 ENSP00000323183 ENST00000325144	Q8N680 [Direct mapping] Zinc finger and BTB domain-containing protein 2 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	514 aa 57.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.