Tissue expression of ACBD4 - Summary - The Human Protein Atlas

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ACBD4

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ACBD4
Gene description	Acyl-CoA binding domain containing 4
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues, most abundant in liver, duodenum and small intestine.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA051772
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ACBD4 (HGNC Symbol)
Synonyms	FLJ13322
Description	Acyl-CoA binding domain containing 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the acyl-coenzyme A binding domain containing protein family. All family members contain the conserved acyl-Coenzyme A binding domain, which binds acyl-CoA thiol esters. They are thought to play roles in acyl-CoA dependent lipid metabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Chromosome	17
Cytoband	q21.31
Chromosome location (bp)	45132600 - 45144181
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000181513 (version 83.38)
Entrez gene	79777
UniProt	Q8NC06 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NC06
Antibodypedia	ACBD4 antibodies

PROTEIN BROWSER

ACBD4-001	ACBD4-002	ACBD4-004	ACBD4-005	ACBD4-006	ACBD4-007	ACBD4-201	ACBD4-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACBD4-001 ENSP00000465610 ENST00000591859	Q8NC06 [Direct mapping] Acyl-CoA-binding domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0008289 [lipid binding] Show all	341 aa 37.8 kDa	No	0
ACBD4-002 ENSP00000465484 ENST00000586346	Q8NC06 [Direct mapping] Acyl-CoA-binding domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0008289 [lipid binding] Show all	341 aa 37.8 kDa	No	0
ACBD4-004 ENSP00000381367 ENST00000398322	Q8NC06 [Direct mapping] Acyl-CoA-binding domain-containing protein 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0008289 [lipid binding] Show all	305 aa 34.8 kDa	No	1
ACBD4-005 ENSP00000466305 ENST00000592162	K7EM05 [Direct mapping] Acyl-CoA-binding domain-containing protein 4; Acyl-Coenzyme A binding domain containing 4, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] Show all	269 aa 29.7 kDa	No	0
ACBD4-006 ENSP00000366154 ENST00000376955	Q8NC06 [Direct mapping] Acyl-CoA-binding domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0008289 [lipid binding] Show all	268 aa 30.3 kDa	No	0
ACBD4-007 ENSP00000314440 ENST00000321854	Q8NC06 [Direct mapping] Acyl-CoA-binding domain-containing protein 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0008289 [lipid binding] Show all	305 aa 34.8 kDa	No	1
ACBD4-201 ENSP00000405969 ENST00000431281	Q8NC06 [Direct mapping] Acyl-CoA-binding domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0008289 [lipid binding] Show all	341 aa 37.8 kDa	No	0
ACBD4-202 ENSP00000482750 ENST00000619916	Q8NC06 [Direct mapping] Acyl-CoA-binding domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0008289 [lipid binding] Show all	268 aa 30.3 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.