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Cytoplasmic staining in most malignant cells at variable intensity. Strong staining in several cases of malignant gliomas and lymphomas and in a few cases of colo-rectal, pancreatic cancers. Most cases of squamous cell carcinomas and renal cancers were either negative or weakly stained.
GENE INFORMATION
Gene name
YBEY (HGNC Symbol)
Synonyms
C21orf57
Description
YbeY metallopeptidase (putative) (HGNC Symbol)
Entrez gene summary
This gene encodes a highly conserved metalloprotein. A similar protein in bacteria acts as an endoribonuclease, and is thought to function in ribosomal RNA maturation and ribosome assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]