Cell atlas - YBEY - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

YBEY

TISSUE

premium

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	YBEY
Gene description	YbeY metallopeptidase (putative)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (validated)

DATA RELIABILITY
Reliability score	Validated based on 1 antibody. HPA016593
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (validated)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA016593	A-431	Nucleoplasm
	HPA016593	U-2 OS	Nucleoplasm
	HPA016593	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	YBEY (HGNC Symbol)
Synonyms	C21orf57
Description	YbeY metallopeptidase (putative) (HGNC Symbol)
Entrez gene summary	This gene encodes a highly conserved metalloprotein. A similar protein in bacteria acts as an endoribonuclease, and is thought to function in ribosomal RNA maturation and ribosome assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Chromosome	21
Cytoband	q22.3
Chromosome location (bp)	46286337 - 46297751
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000182362 (version 83.38)
Entrez gene	54059
UniProt	P58557 (UniProt - Evidence at protein level)
neXtProt	NX_P58557
Antibodypedia	YBEY antibodies

PROTEIN BROWSER

YBEY-001	YBEY-002	YBEY-003	YBEY-004	YBEY-007	YBEY-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
YBEY-001 ENSP00000329614 ENST00000329319	P58557 [Direct mapping] Putative ribonuclease Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004222 [metalloendopeptidase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0006364 [rRNA processing] GO:0006508 [proteolysis] GO:0046872 [metal ion binding] Show all	167 aa 19.3 kDa	No	0
YBEY-002 ENSP00000340675 ENST00000339195	P58557 [Direct mapping] Putative ribonuclease Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004222 [metalloendopeptidase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006364 [rRNA processing] GO:0006508 [proteolysis] GO:0046872 [metal ion binding] Show all	124 aa 14.3 kDa	No	0
YBEY-003 ENSP00000380808 ENST00000397694	P58557 [Direct mapping] Putative ribonuclease Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004222 [metalloendopeptidase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006364 [rRNA processing] GO:0006508 [proteolysis] GO:0046872 [metal ion binding] Show all	122 aa 14 kDa	No	0
YBEY-004 ENSP00000380806 ENST00000397692	P58557 [Direct mapping] Putative ribonuclease Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004222 [metalloendopeptidase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006364 [rRNA processing] GO:0006508 [proteolysis] GO:0046872 [metal ion binding] Show all	79 aa 8.9 kDa	No	0
YBEY-007 ENSP00000380813 ENST00000397701	P58557 [Direct mapping] Putative ribonuclease Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004222 [metalloendopeptidase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006364 [rRNA processing] GO:0006508 [proteolysis] GO:0046872 [metal ion binding] Show all	167 aa 19.3 kDa	No	0
YBEY-008 ENSP00000380805 ENST00000397691	P58557 [Direct mapping] Putative ribonuclease Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004222 [metalloendopeptidase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006364 [rRNA processing] GO:0006508 [proteolysis] GO:0046872 [metal ion binding] Show all	167 aa 19.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.