Cell atlas - SLC25A21 - The Human Protein Atlas

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SLC25A21

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SLC25A21
Gene description	Solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
Protein class	Predicted intracellular proteins Transporters
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (Karpas-707, K-562, HEK 293)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (Karpas-707, K-562, HEK 293) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SLC25A21 (HGNC Symbol)
Synonyms	ODC, ODC1
Description	Solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 (HGNC Symbol)
Entrez gene summary	SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004]
Chromosome	14
Cytoband	q13.3
Chromosome location (bp)	36677921 - 37172866
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183032 (version 83.38)
Entrez gene	89874
UniProt	Q9BQT8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BQT8
Antibodypedia	SLC25A21 antibodies

PROTEIN BROWSER

SLC25A21-001	SLC25A21-004	SLC25A21-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC25A21-001 ENSP00000329452 ENST00000331299	Q9BQT8 [Direct mapping] Mitochondrial 2-oxodicarboxylate carrier Show all	Transporters Electrochemical Potential-driven transporters MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0006554 [lysine catabolic process] GO:0016021 [integral component of membrane] GO:0034641 [cellular nitrogen compound metabolic process] GO:0044281 [small molecule metabolic process] GO:0055085 [transmembrane transport] Show all	299 aa 33.3 kDa	No	0
SLC25A21-004 ENSP00000451873 ENST00000555449	Q9BQT8 [Direct mapping] Mitochondrial 2-oxodicarboxylate carrier Show all	Transporters Electrochemical Potential-driven transporters MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005743 [mitochondrial inner membrane] GO:0006554 [lysine catabolic process] GO:0016021 [integral component of membrane] GO:0034641 [cellular nitrogen compound metabolic process] GO:0044281 [small molecule metabolic process] GO:0055085 [transmembrane transport] Show all	298 aa 33.1 kDa	No	0
SLC25A21-201 ENSP00000481445 ENST00000622765	A0A087WY12 [Direct mapping] Mitochondrial 2-oxodicarboxylate carrier Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0016021 [integral component of membrane] Show all	234 aa 26.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.