Expression of ARHGEF37 in cancer - Summary

CANCER ATLAS

Gene description

Rho guanine nucleotide exchange factor (GEF) 37

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA043885	HPA053487

GENE INFORMATION
Gene name	ARHGEF37 (HGNC Symbol)
Synonyms	FLJ41603
Description	Rho guanine nucleotide exchange factor (GEF) 37 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q32
Chromosome location (bp)	149551947 - 149634968
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183111 (version 83.38)
Entrez gene	389337
UniProt	A1IGU5 (UniProt - Evidence at transcript level)
neXtProt	NX_A1IGU5
Antibodypedia	ARHGEF37 antibodies

PROTEIN BROWSER

ARHGEF37-001	ARHGEF37-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARHGEF37-001 ENSP00000328083 ENST00000333677	A1IGU5 [Direct mapping] Rho guanine nucleotide exchange factor 37 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005089 [Rho guanyl-nucleotide exchange factor activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0035023 [regulation of Rho protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	675 aa 76.3 kDa	No	0
ARHGEF37-002 ENSP00000425621 ENST00000505810	D6RJH4 [Direct mapping] Rho guanine nucleotide exchange factor 37 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005089 [Rho guanyl-nucleotide exchange factor activity] GO:0035023 [regulation of Rho protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	103 aa 11.7 kDa	No	0