Expression of HMCES in cancer - Summary

CANCER ATLAS

Gene description

5-hydroxymethylcytosine (hmC) binding, ES cell-specific

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Cervical cancer

STAINING SUMMARY

HPA044968

GENE INFORMATION
Gene name	HMCES (HGNC Symbol)
Synonyms	C3orf37, DC12, SRAPD1
Description	5-hydroxymethylcytosine (hmC) binding, ES cell-specific (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q21.3
Chromosome location (bp)	129278828 - 129306186
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183624 (version 83.38)
Entrez gene	56941
UniProt	Q96FZ2 (UniProt - Evidence at protein level)
neXtProt	NX_Q96FZ2
Antibodypedia	HMCES antibodies

PROTEIN BROWSER

HMCES-001	HMCES-002	HMCES-003	HMCES-004	HMCES-005	HMCES-006	HMCES-007	HMCES-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HMCES-001 ENSP00000372955 ENST00000383463	Q96FZ2 [Direct mapping] Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0006508 [proteolysis] GO:0008233 [peptidase activity] Show all	354 aa 40.6 kDa	No	0
HMCES-002 ENSP00000374385 ENST00000389735	Q96FZ2 [Direct mapping] Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0006508 [proteolysis] GO:0008233 [peptidase activity] Show all	354 aa 40.6 kDa	No	0
HMCES-003 ENSP00000426215 ENST00000502878	Q96FZ2 [Direct mapping] Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0006508 [proteolysis] GO:0008233 [peptidase activity] Show all	354 aa 40.6 kDa	No	0
HMCES-004 ENSP00000392966 ENST00000417226	E7EMP6 [Direct mapping] Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		312 aa 35.6 kDa	No	0
HMCES-005 ENSP00000423132 ENST00000509042	D6R9T3 [Direct mapping] Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		282 aa 32.1 kDa	No	0
HMCES-006 ENSP00000426276 ENST00000510314	D6RGK7 [Direct mapping] Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		183 aa 20.6 kDa	No	0
HMCES-007 ENSP00000421895 ENST00000511665	D6RAI0 [Direct mapping] Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		140 aa 16 kDa	No	0
HMCES-009 ENSP00000424594 ENST00000509551	D6RAZ3 [Direct mapping] Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		233 aa 26.9 kDa	No	0