Expression of COA3 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

COA3

TISSUE

premium

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Cytochrome c oxidase assembly factor 3

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA031966

GENE INFORMATION
Gene name	COA3 (HGNC Symbol)
Synonyms	CCDC56, HSPC009, MITRAC12
Description	Cytochrome c oxidase assembly factor 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the cytochrome c oxidase assembly factor family. Studies of a related gene in fly suggest that the encoded protein is localized to mitochondria and is essential for cytochrome c oxidase function. [provided by RefSeq, Nov 2012]
Chromosome	17
Cytoband	q21.2
Chromosome location (bp)	42795147 - 42798704
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183978 (version 83.38)
Entrez gene	28958
UniProt	Q9Y2R0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2R0
Antibodypedia	COA3 antibodies

PROTEIN BROWSER

COA3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COA3-001 ENSP00000354762 ENST00000328434	Q9Y2R0 [Direct mapping] Cytochrome c oxidase assembly factor 3 homolog, mitochondrial A0A024R1X4 [Target identity:100%; Query identity:100%] HCG16955, isoform CRA_b Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0031305 [integral component of mitochondrial inner membrane] GO:0033617 [mitochondrial respiratory chain complex IV assembly] GO:0070131 [positive regulation of mitochondrial translation] Show all	106 aa 11.7 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.