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Several cases of testicular cancers showed weak cytoplasmic positivity. The remaining malignant cells were mainly negative.
GENE INFORMATION
Gene name
GDF3
Synonyms
Description
Growth differentiation factor 3 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. [provided by RefSeq, Jul 2008]