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APOBR

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GENERAL INFORMATION

Gene name

 APOBR

Gene description

 Apolipoprotein B receptor

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (HMC-1, HEL, U-937, NB-4)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HMC-1, HEL, U-937, NB-4)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 APOBR (HGNC Symbol)

Synonyms

 APOB100R, APOB48R

Description

 Apolipoprotein B receptor (HGNC Symbol)

Entrez gene summary

 Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 p12.1

Chromosome location (bp)

 28494649 - 28498970

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000184730 (version 83.38)

Entrez gene

 55911

UniProt

 Q0VD83 (UniProt - Evidence at protein level)

neXtProt

 NX_Q0VD83

Antibodypedia

 APOBR antibodies

PROTEIN BROWSER
APOBR-001
APOBR-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
APOBR-001
ENSP00000457539
ENST00000564831
Q0VD83 [Direct mapping]
Apolipoprotein B receptor
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005886 [plasma membrane]
GO:0006641 [triglyceride metabolic process]
GO:0006869 [lipid transport]
GO:0006898 [receptor-mediated endocytosis]
GO:0008203 [cholesterol metabolic process]
GO:0016020 [membrane]
GO:0030229 [very-low-density lipoprotein particle receptor activity]
GO:0034361 [very-low-density lipoprotein particle]
GO:0034362 [low-density lipoprotein particle]
GO:0042627 [chylomicron]
Show all
 1097 aa
115.6 kDa 		No 0
APOBR-201
ENSP00000416094
ENST00000431282
Q0VD83 [Direct mapping]
Apolipoprotein B receptor
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005886 [plasma membrane]
GO:0006641 [triglyceride metabolic process]
GO:0006869 [lipid transport]
GO:0006898 [receptor-mediated endocytosis]
GO:0008203 [cholesterol metabolic process]
GO:0016020 [membrane]
GO:0030229 [very-low-density lipoprotein particle receptor activity]
GO:0034361 [very-low-density lipoprotein particle]
GO:0034362 [low-density lipoprotein particle]
GO:0042627 [chylomicron]
Show all
 1088 aa
114.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.