Tissue expression of TUSC5 - Summary - The Human Protein Atlas

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TUSC5

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TUSC5
Gene description	Tumor suppressor candidate 5
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (adipose tissue)
GTEx:	Group enriched (adipose tissue, breast)
FANTOM5:	Group enriched (adipose tissue, breast)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several different tissue, including adipose tissue and renal tubules.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA050825
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (adipose tissue)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (adipose tissue, breast)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (adipose tissue, breast)

GENE INFORMATION
Gene name	TUSC5 (HGNC Symbol)
Synonyms	IFITMD3, LOST1
Description	Tumor suppressor candidate 5 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.3
Chromosome location (bp)	1279663 - 1300987
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184811 (version 83.38)
Entrez gene	286753
UniProt	Q8IXB3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IXB3
Antibodypedia	TUSC5 antibodies

PROTEIN BROWSER

TUSC5-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TUSC5-001 ENSP00000329548 ENST00000333813	Q8IXB3 [Direct mapping] Tumor suppressor candidate 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0009607 [response to biotic stimulus] GO:0016021 [integral component of membrane] Show all	177 aa 19.3 kDa	No	2

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.