Expression of ZFP90 in cancer - Summary

CANCER ATLAS

Gene description

ZFP90 zinc finger protein

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA029017

GENE INFORMATION
Gene name	ZFP90 (HGNC Symbol)
Synonyms	KIAA1954, NK10, ZNF756
Description	ZFP90 zinc finger protein (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the zinc finger protein family that modulates gene expression. The encoded protein derepresses the transcription of certain fetal cardiac genes and may contribute to the genetic reprogramming that occurs during the development of heart failure. Genome wide association studies have identified this gene among ulcerative colitis risk loci. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015]
Chromosome	16
Cytoband	q22.1
Chromosome location (bp)	68530090 - 68576072
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184939 (version 83.38)
Entrez gene	146198
UniProt	Q8TF47 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TF47
Antibodypedia	ZFP90 antibodies

PROTEIN BROWSER

ZFP90-001	ZFP90-005	ZFP90-006	ZFP90-008	ZFP90-010	ZFP90-013	ZFP90-018	ZFP90-019	ZFP90-022	ZFP90-023	ZFP90-201	ZFP90-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZFP90-001 ENSP00000460547 ENST00000570495	Q8TF47 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043392 [negative regulation of DNA binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	636 aa 73 kDa	No	0
ZFP90-005 ENSP00000458323 ENST00000569109	I3L0T2 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	33 aa 3.9 kDa	No	0
ZFP90-006 ENSP00000463193 ENST00000564323	J3QKQ8 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	93 aa 10.9 kDa	No	0
ZFP90-008 ENSP00000458051 ENST00000562156	H3BVC6 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	103 aa 12 kDa	No	0
ZFP90-010 ENSP00000454418 ENST00000563169	Q8TF47 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	636 aa 73 kDa	No	0
ZFP90-013 ENSP00000459944 ENST00000573685	H3BVC6 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	103 aa 12 kDa	No	0
ZFP90-018 ENSP00000458920 ENST00000571382	I3L1L4 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	45 aa 5.2 kDa	No	0
ZFP90-019 ENSP00000458410 ENST00000573113	I3L0X7 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	102 aa 11.9 kDa	No	0
ZFP90-022 ENSP00000459846 ENST00000573161	I3L2Q3 [Direct mapping] Zinc finger protein 90 homolog Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		52 aa 5.4 kDa	No	0
ZFP90-023 ENSP00000460560 ENST00000576305	I3L3M0 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	47 aa 5.5 kDa	No	0
ZFP90-201 ENSP00000381304 ENST00000398253	Q8TF47 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	636 aa 73 kDa	No	0
ZFP90-202 ENSP00000480309 ENST00000611381	Q8TF47 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	113 aa 13 kDa	No	0