Cell atlas - ZFP90 - The Human Protein Atlas

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ZFP90

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Centrosome
	Plasma membrane
	Vesicles

Human cell
	Centrosome
	Plasma Membrane
	Vesicles

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GENERAL INFORMATION
Gene name	ZFP90
Gene description	ZFP90 zinc finger protein
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	12
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the plasma membrane, centrosome & vesicles.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved), Plasma membrane (approved), Centrosome (approved)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA029017
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the plasma membrane, centrosome & vesicles.

Main location

Vesicles (approved), Plasma membrane (approved), Centrosome (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA029017	A-431	Vesicles
			Plasma membrane
			Centrosome
	HPA029017	U-2 OS	Vesicles
			Plasma membrane
			Centrosome
	HPA029017	U-251 MG	Vesicles
	HPA029017	U-251 MG	Centrosome

GENE INFORMATION
Gene name	ZFP90 (HGNC Symbol)
Synonyms	KIAA1954, NK10, ZNF756
Description	ZFP90 zinc finger protein (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the zinc finger protein family that modulates gene expression. The encoded protein derepresses the transcription of certain fetal cardiac genes and may contribute to the genetic reprogramming that occurs during the development of heart failure. Genome wide association studies have identified this gene among ulcerative colitis risk loci. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015]
Chromosome	16
Cytoband	q22.1
Chromosome location (bp)	68530090 - 68576072
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184939 (version 83.38)
Entrez gene	146198
UniProt	Q8TF47 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TF47
Antibodypedia	ZFP90 antibodies

PROTEIN BROWSER

ZFP90-001	ZFP90-005	ZFP90-006	ZFP90-008	ZFP90-010	ZFP90-013	ZFP90-018	ZFP90-019	ZFP90-022	ZFP90-023	ZFP90-201	ZFP90-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZFP90-001 ENSP00000460547 ENST00000570495	Q8TF47 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043392 [negative regulation of DNA binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	636 aa 73 kDa	No	0
ZFP90-005 ENSP00000458323 ENST00000569109	I3L0T2 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	33 aa 3.9 kDa	No	0
ZFP90-006 ENSP00000463193 ENST00000564323	J3QKQ8 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	93 aa 10.9 kDa	No	0
ZFP90-008 ENSP00000458051 ENST00000562156	H3BVC6 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	103 aa 12 kDa	No	0
ZFP90-010 ENSP00000454418 ENST00000563169	Q8TF47 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	636 aa 73 kDa	No	0
ZFP90-013 ENSP00000459944 ENST00000573685	H3BVC6 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	103 aa 12 kDa	No	0
ZFP90-018 ENSP00000458920 ENST00000571382	I3L1L4 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	45 aa 5.2 kDa	No	0
ZFP90-019 ENSP00000458410 ENST00000573113	I3L0X7 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	102 aa 11.9 kDa	No	0
ZFP90-022 ENSP00000459846 ENST00000573161	I3L2Q3 [Direct mapping] Zinc finger protein 90 homolog Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		52 aa 5.4 kDa	No	0
ZFP90-023 ENSP00000460560 ENST00000576305	I3L3M0 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	47 aa 5.5 kDa	No	0
ZFP90-201 ENSP00000381304 ENST00000398253	Q8TF47 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	636 aa 73 kDa	No	0
ZFP90-202 ENSP00000480309 ENST00000611381	Q8TF47 [Direct mapping] Zinc finger protein 90 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	113 aa 13 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.