Cell atlas - SLC36A2 - The Human Protein Atlas

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SLC36A2

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SLC36A2
Gene description	Solute carrier family 36 (proton/amino acid symporter), member 2
Protein class	Disease related genes Potential drug targets Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SLC36A2 (HGNC Symbol)
Synonyms	PAT2, TRAMD1, tramdorin
Description	Solute carrier family 36 (proton/amino acid symporter), member 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria. [provided by RefSeq, Sep 2010]
Chromosome	5
Cytoband	q33.1
Chromosome location (bp)	151314978 - 151347590
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000186335 (version 83.38)
Entrez gene	153201
UniProt	Q495M3 (UniProt - Evidence at protein level)
neXtProt	NX_Q495M3
Antibodypedia	SLC36A2 antibodies

PROTEIN BROWSER

SLC36A2-001	SLC36A2-004	SLC36A2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC36A2-001 ENSP00000334223 ENST00000335244	Q495M3 [Direct mapping] Proton-coupled amino acid transporter 2 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005280 [hydrogen:amino acid symporter activity] GO:0005774 [vacuolar membrane] GO:0005886 [plasma membrane] GO:0006811 [ion transport] GO:0006865 [amino acid transport] GO:0015078 [hydrogen ion transmembrane transporter activity] GO:0015180 [L-alanine transmembrane transporter activity] GO:0015187 [glycine transmembrane transporter activity] GO:0015193 [L-proline transmembrane transporter activity] GO:0015808 [L-alanine transport] GO:0015816 [glycine transport] GO:0015824 [proline transport] GO:0015992 [proton transport] GO:0016021 [integral component of membrane] GO:0035524 [proline transmembrane transport] GO:0055085 [transmembrane transport] GO:0070062 [extracellular exosome] GO:1902600 [hydrogen ion transmembrane transport] Show all	483 aa 53.2 kDa	No	>9
SLC36A2-004 ENSP00000430535 ENST00000521967	E5RJJ5 [Direct mapping] Proton-coupled amino acid transporter 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005280 [hydrogen:amino acid symporter activity] GO:0005774 [vacuolar membrane] GO:0015078 [hydrogen ion transmembrane transporter activity] GO:0015180 [L-alanine transmembrane transporter activity] GO:0015193 [L-proline transmembrane transporter activity] GO:0015808 [L-alanine transport] GO:0015816 [glycine transport] GO:0015992 [proton transport] GO:0016021 [integral component of membrane] GO:0035524 [proline transmembrane transport] GO:1902600 [hydrogen ion transmembrane transport] Show all	395 aa 43.8 kDa	No	8
SLC36A2-005 ENSP00000428634 ENST00000523044	H0YB43 [Direct mapping] Proton-coupled amino acid transporter 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005280 [hydrogen:amino acid symporter activity] GO:0005774 [vacuolar membrane] GO:0015078 [hydrogen ion transmembrane transporter activity] GO:0015180 [L-alanine transmembrane transporter activity] GO:0015193 [L-proline transmembrane transporter activity] GO:0015808 [L-alanine transport] GO:0015816 [glycine transport] GO:0015992 [proton transport] GO:0016021 [integral component of membrane] GO:0035524 [proline transmembrane transport] GO:1902600 [hydrogen ion transmembrane transport] Show all	107 aa 11.4 kDa	No	2

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.