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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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SPATC1
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CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Spermatogenesis and centriole associated 1

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA039590
HPA040220

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Hepatocellular carcinoma showed moderate to strong cytoplasmic and occasional nuclear staining. Several pancreatic, gastric, renal and colorectal cancers showed moderate to strong cytoplasmic positivity with nuclear and/or membranous staining in a few cases. Malignant cells in general were weakly stained or negative.

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Most malignancies exhibited moderate to strong membranous and/or cytoplasmic positivity. Several cases of malignant lymphomas, colorectal, gastric and liver cancers were weakly stained or negative.

GENE INFORMATION

Gene name

SPATC1 (HGNC Symbol)

Synonyms

MGC61633, SPATA15, SPERIOLIN

Description

Spermatogenesis and centriole associated 1 (HGNC Symbol)

Entrez gene summary

Chromosome

8

Cytoband

q24.3

Chromosome location (bp)

144012414 - 144047085

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186583 (version 83.38)

Entrez gene

375686

UniProt

Q76KD6 (UniProt - Evidence at transcript level)

neXtProt

NX_Q76KD6

Antibodypedia

SPATC1 antibodies

PROTEIN BROWSER

SPATC1-001
SPATC1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SPATC1-001
ENSP00000366690
ENST00000377470
Q76KD6 [Direct mapping]
Speriolin
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
Show all
591 aa
62.4 kDa
No 0
SPATC1-002
ENSP00000387613
ENST00000447830
Q76KD6 [Direct mapping]
Speriolin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
Show all
441 aa
45.4 kDa
No 0

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