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Hepatocellular carcinoma showed moderate to strong cytoplasmic and occasional nuclear staining. Several pancreatic, gastric, renal and colorectal cancers showed moderate to strong cytoplasmic positivity with nuclear and/or membranous staining in a few cases. Malignant cells in general were weakly stained or negative.
Most malignancies exhibited moderate to strong membranous and/or cytoplasmic positivity. Several cases of malignant lymphomas, colorectal, gastric and liver cancers were weakly stained or negative.
GENE INFORMATION
Gene name
SPATC1 (HGNC Symbol)
Synonyms
MGC61633, SPATA15, SPERIOLIN
Description
Spermatogenesis and centriole associated 1 (HGNC Symbol)