Tissue expression of RNF220 - Summary - The Human Protein Atlas

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RNF220

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	RNF220
Gene description	Ring finger protein 220
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA027578
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

N/A

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	RNF220 (HGNC Symbol)
Synonyms	C1orf164, FLJ10597
Description	Ring finger protein 220 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p34.1
Chromosome location (bp)	44405194 - 44651724
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187147 (version 83.38)
Entrez gene	55182
UniProt	Q5VTB9 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VTB9
Antibodypedia	RNF220 antibodies

PROTEIN BROWSER

RNF220-001	RNF220-002	RNF220-010	RNF220-013	RNF220-014	RNF220-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RNF220-001 ENSP00000347548 ENST00000355387	Q5VTB9 [Direct mapping] E3 ubiquitin-protein ligase RNF220 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008270 [zinc ion binding] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0051865 [protein autoubiquitination] GO:0061630 [ubiquitin protein ligase activity] GO:0090263 [positive regulation of canonical Wnt signaling pathway] Show all	566 aa 62.8 kDa	Yes	0
RNF220-002 ENSP00000354872 ENST00000361799	Q5VTB9 [Direct mapping] E3 ubiquitin-protein ligase RNF220 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008270 [zinc ion binding] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0051865 [protein autoubiquitination] GO:0090263 [positive regulation of canonical Wnt signaling pathway] Show all	566 aa 62.8 kDa	Yes	0
RNF220-010 ENSP00000411541 ENST00000453863	H0Y7B1 [Direct mapping] E3 ubiquitin-protein ligase RNF220 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		121 aa 13.8 kDa	No	0
RNF220-013 ENSP00000388533 ENST00000440132	Q5TDE7 [Direct mapping] E3 ubiquitin-protein ligase RNF220 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		259 aa 29.3 kDa	No	0
RNF220-014 ENSP00000335580 ENST00000335497	Q5TDE8 [Direct mapping] E3 ubiquitin-protein ligase RNF220 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		260 aa 29.2 kDa	No	0
RNF220-201 ENSP00000361321 ENST00000372247	Q5VTB9 [Direct mapping] E3 ubiquitin-protein ligase RNF220 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008270 [zinc ion binding] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0051865 [protein autoubiquitination] GO:0090263 [positive regulation of canonical Wnt signaling pathway] Show all	566 aa 62.8 kDa	Yes	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.