Expression of B3GLCT in cancer - Summary

CANCER ATLAS

Gene description

Beta 3-glucosyltransferase

Protein class

Disease related genes, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA017664

GENE INFORMATION
Gene name	B3GLCT (HGNC Symbol)
Synonyms	B3GALTL, B3Glc-T, B3GTL
Description	Beta 3-glucosyltransferase (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009]
Chromosome	13
Cytoband	q12.3
Chromosome location (bp)	31199936 - 31332276
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187676 (version 83.38)
Entrez gene	145173
UniProt	Q6Y288 (UniProt - Evidence at protein level)
neXtProt	NX_Q6Y288
Antibodypedia	B3GLCT antibodies

PROTEIN BROWSER

B3GLCT-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
B3GLCT-001 ENSP00000343002 ENST00000343307	Q6Y288 [Direct mapping] Beta-1,3-glucosyltransferase Show all	THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005789 [endoplasmic reticulum membrane] GO:0006004 [fucose metabolic process] GO:0006493 [protein O-linked glycosylation] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016757 [transferase activity, transferring glycosyl groups] GO:0036066 [protein O-linked fucosylation] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] Show all	498 aa 56.6 kDa	Yes	0