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B3GLCT

GENERAL INFORMATION

Gene name

 B3GLCT

Gene description

 Beta 3-glucosyltransferase

Protein class

 Disease related genes
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA017664
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 B3GLCT (HGNC Symbol)

Synonyms

 B3GALTL, B3Glc-T, B3GTL

Description

 Beta 3-glucosyltransferase (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009]

Chromosome

 13

Cytoband

 q12.3

Chromosome location (bp)

 31199936 - 31332276

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000187676 (version 83.38)

Entrez gene

 145173

UniProt

 Q6Y288 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6Y288

Antibodypedia

 B3GLCT antibodies

PROTEIN BROWSER
B3GLCT-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
B3GLCT-001
ENSP00000343002
ENST00000343307
Q6Y288 [Direct mapping]
Beta-1,3-glucosyltransferase
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   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005789 [endoplasmic reticulum membrane]
GO:0006004 [fucose metabolic process]
GO:0006493 [protein O-linked glycosylation]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016757 [transferase activity, transferring glycosyl groups]
GO:0036066 [protein O-linked fucosylation]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
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 498 aa
56.6 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.