Expression of LAMTOR4 in cancer - Summary

CANCER ATLAS

Gene description

Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA020998

GENE INFORMATION
Gene name	LAMTOR4 (HGNC Symbol)
Synonyms	C7orf59
Description	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	100148907 - 100155944
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188186 (version 83.38)
Entrez gene	389541
UniProt	Q0VGL1 (UniProt - Evidence at protein level)
neXtProt	NX_Q0VGL1
Antibodypedia	LAMTOR4 antibodies

PROTEIN BROWSER

LAMTOR4-001	LAMTOR4-002	LAMTOR4-003	LAMTOR4-005	LAMTOR4-007	LAMTOR4-008	LAMTOR4-009	LAMTOR4-011	LAMTOR4-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LAMTOR4-001 ENSP00000343118 ENST00000341942	Q0VGL1 [Direct mapping] Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR4, N-terminally processed Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005515 [protein binding] GO:0005764 [lysosome] GO:0005765 [lysosomal membrane] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0007050 [cell cycle arrest] GO:0008286 [insulin receptor signaling pathway] GO:0008361 [regulation of cell size] GO:0010467 [gene expression] GO:0016236 [macroautophagy] GO:0032008 [positive regulation of TOR signaling] GO:0032947 [protein complex scaffold] GO:0043231 [intracellular membrane-bounded organelle] GO:0043547 [positive regulation of GTPase activity] GO:0061462 [protein localization to lysosome] GO:0071230 [cellular response to amino acid stimulus] GO:0071986 [Ragulator complex] Show all	99 aa 10.7 kDa	No	0
LAMTOR4-002 ENSP00000477680 ENST00000474141	A0A087WT92 [Direct mapping] Ragulator complex protein LAMTOR4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		72 aa 7.9 kDa	No	0
LAMTOR4-003 ENSP00000479176 ENST00000460732	A0A087WV46 [Direct mapping] Ragulator complex protein LAMTOR4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 8.9 kDa	No	0
LAMTOR4-005 ENSP00000387926 ENST00000441173	C9JXA7 [Direct mapping] Ragulator complex protein LAMTOR4 Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		137 aa 14.3 kDa	No	0
LAMTOR4-007 ENSP00000478095 ENST00000468582	A0A087WVU0 [Direct mapping] Ragulator complex protein LAMTOR4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		41 aa 4.7 kDa	No	0
LAMTOR4-008 ENSP00000479500 ENST00000488241	A0A087WVK8 [Direct mapping] Ragulator complex protein LAMTOR4 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		24 aa 2.8 kDa	No	0
LAMTOR4-009 ENSP00000479685 ENST00000473459	A0A087WVU0 [Direct mapping] Ragulator complex protein LAMTOR4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		41 aa 4.7 kDa	No	0
LAMTOR4-011 ENSP00000480432 ENST00000466498	A0A087WWR0 [Direct mapping] Ragulator complex protein LAMTOR4 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		20 aa 2.3 kDa	No	0
LAMTOR4-012 ENSP00000481202 ENST00000490633	A0A087WXQ3 [Direct mapping] Ragulator complex protein LAMTOR4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		19 aa 2.1 kDa	No	0