Cell atlas - LIPI - The Human Protein Atlas

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LIPI

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	LIPI
Gene description	Lipase, member I
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	LIPI (HGNC Symbol)
Synonyms	CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5
Description	Lipase, member I (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. This gene is also expressed at high levels in Ewing family tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Chromosome	21
Cytoband	q11.2
Chromosome location (bp)	14108813 - 14210891
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188992 (version 83.38)
Entrez gene	149998
UniProt	Q6XZB0 (UniProt - Evidence at protein level)
neXtProt	NX_Q6XZB0
Antibodypedia	LIPI antibodies

PROTEIN BROWSER

LIPI-001	LIPI-002	LIPI-201	LIPI-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LIPI-001 ENSP00000343331 ENST00000344577	Q6XZB0 [Direct mapping] Lipase member I Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0004620 [phospholipase activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0005886 [plasma membrane] GO:0006629 [lipid metabolic process] GO:0008201 [heparin binding] GO:0016020 [membrane] GO:0016042 [lipid catabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	481 aa 55.2 kDa	No	0
LIPI-002 ENSP00000383072 ENST00000400211	H0Y3S0 [Direct mapping] Lipase member I Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0008152 [metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	141 aa 15.7 kDa	No	0
LIPI-201 ENSP00000440381 ENST00000536861	Q6XZB0 [Direct mapping] Lipase member I Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0004620 [phospholipase activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0005886 [plasma membrane] GO:0006629 [lipid metabolic process] GO:0008201 [heparin binding] GO:0016020 [membrane] GO:0016042 [lipid catabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	451 aa 51.8 kDa	No	0
LIPI-202 ENSP00000482652 ENST00000614229	A0A087WZG8 [Direct mapping] Lipase member I Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0006629 [lipid metabolic process] GO:0008152 [metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	421 aa 48.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.