Expression of SIRPB2 in cancer - Summary - The Human Protein Atlas

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SIRPB2

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Signal-regulatory protein beta 2

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Ovarian cancer

STAINING SUMMARY

HPA011548	HPA048032

GENE INFORMATION
Gene name	SIRPB2 (HGNC Symbol)
Synonyms	dJ776F14.2, PTPN1L, PTPNS1L3
Description	Signal-regulatory protein beta 2 (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	p13
Chromosome location (bp)	1470741 - 1491587
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196209 (version 83.38)
Entrez gene	284759
UniProt	Q5JXA9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5JXA9
Antibodypedia	SIRPB2 antibodies

PROTEIN BROWSER

SIRPB2-001	SIRPB2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SIRPB2-001 ENSP00000352849 ENST00000359801	Q5JXA9 [Direct mapping] Signal-regulatory protein beta-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	342 aa 37 kDa	Yes	1
SIRPB2-005 ENSP00000402438 ENST00000444444	Q5JXA9 [Direct mapping] Signal-regulatory protein beta-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	244 aa 25.8 kDa	Yes	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.