Expression of ZNF124 in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger protein 124

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA031127

GENE INFORMATION
Gene name	ZNF124 (HGNC Symbol)
Synonyms	HZF-16, HZF16
Description	Zinc finger protein 124 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein with an amino-terminal KRAB-A box and multiple repeated Kruppel-type (C2H2) zinc finger motifs at its carboxy terminus. The encoded protein may function as a transcription factor. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and results in inhibition of apoptotic cell death induced by irradiation or exposure to etoposide. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2014]
Chromosome	1
Cytoband	q44
Chromosome location (bp)	247121975 - 247172016
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196418 (version 83.38)
Entrez gene	7678
UniProt	Q15973 (UniProt - Evidence at protein level)
neXtProt	NX_Q15973
Antibodypedia	ZNF124 antibodies

PROTEIN BROWSER

ZNF124-001	ZNF124-003	ZNF124-004	ZNF124-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF124-001 ENSP00000462445 ENST00000472531	Q15973 [Direct mapping] Zinc finger protein 124 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	73 aa 8.4 kDa	No	0
ZNF124-003 ENSP00000463191 ENST00000491356	J3QKQ6 [Direct mapping] Zinc finger protein 124 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	77 aa 8.8 kDa	No	0
ZNF124-004 ENSP00000340749 ENST00000340684	Q15973 [Direct mapping] Zinc finger protein 124 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	289 aa 33.3 kDa	No	0
ZNF124-009 ENSP00000440365 ENST00000543802	Q15973 [Direct mapping] Zinc finger protein 124 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	351 aa 40.2 kDa	No	0