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AMZ2

GENERAL INFORMATION

Gene name

 AMZ2

Gene description

 Archaelysin family metallopeptidase 2

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 13
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear and cytoplasmic expression in several tissues, most abundant in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA023299
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 AMZ2

Synonyms

Description

 Archaelysin family metallopeptidase 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 q24.2

Chromosome location (bp)

 68247574 - 68257164

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000196704 (version 83.38)

Entrez gene

 51321

UniProt

 Q86W34 (UniProt - Evidence at protein level)

neXtProt

 NX_Q86W34

Antibodypedia

 AMZ2 antibodies

PROTEIN BROWSER
«
AMZ2-001
AMZ2-002
AMZ2-003
AMZ2-004
AMZ2-006
AMZ2-007
AMZ2-008
AMZ2-009
AMZ2-010
AMZ2-014
AMZ2-015
AMZ2-016
AMZ2-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AMZ2-001
ENSP00000352976
ENST00000359904
Q86W34 [Direct mapping]
Archaemetzincin-2
Show all
Enzymes
   Peptidases
   Metallopeptidases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 360 aa
41.3 kDa 		No 0
AMZ2-002
ENSP00000463012
ENST00000580753
Q86W34 [Direct mapping]
Archaemetzincin-2
Show all
Enzymes
   Peptidases
   Metallopeptidases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 360 aa
41.3 kDa 		No 0
AMZ2-003
ENSP00000376481
ENST00000392720
Q86W34 [Direct mapping]
Archaemetzincin-2
Show all
Enzymes
   Peptidases
   Metallopeptidases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 360 aa
41.3 kDa 		No 0
AMZ2-004
ENSP00000352831
ENST00000359783
Q86W34 [Direct mapping]
Archaemetzincin-2
Show all
Enzymes
   Peptidases
   Metallopeptidases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 302 aa
34.6 kDa 		No 0
AMZ2-006
ENSP00000464133
ENST00000577866
Q86W34 [Direct mapping]
Archaemetzincin-2
Show all
Enzymes
   Peptidases
   Metallopeptidases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 360 aa
41.3 kDa 		No 0
AMZ2-007
ENSP00000464635
ENST00000577985
Q86W34 [Direct mapping]
Archaemetzincin-2
Show all
Enzymes
   Peptidases
   Metallopeptidases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 360 aa
41.3 kDa 		No 0
AMZ2-008
ENSP00000462140
ENST00000577273
J3KRS2 [Direct mapping]
Archaemetzincin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 201 aa
22.9 kDa 		No 0
AMZ2-009
ENSP00000462484
ENST00000580548
J3KSH1 [Direct mapping]
Archaemetzincin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 195 aa
22.3 kDa 		No 0
AMZ2-010
ENSP00000463053
ENST00000584837
J3KTM1 [Direct mapping]
Archaemetzincin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 221 aa
25.4 kDa 		No 0
AMZ2-014
ENSP00000463596
ENST00000579724
J3QLK6 [Direct mapping]
Archaemetzincin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 206 aa
23.5 kDa 		No 0
AMZ2-015
ENSP00000461935
ENST00000584494
J3KRD0 [Direct mapping]
Archaemetzincin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 248 aa
28.4 kDa 		No 0
AMZ2-016
ENSP00000462292
ENST00000580837
J3KS38 [Direct mapping]
Archaemetzincin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 197 aa
22.5 kDa 		No 0
AMZ2-201
ENSP00000483162
ENST00000612294
Q86W34 [Direct mapping]
Archaemetzincin-2
Show all
Enzymes
   Peptidases
   Metallopeptidases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006508 [proteolysis]
GO:0008237 [metallopeptidase activity]
GO:0008270 [zinc ion binding]
Show all
 360 aa
41.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.