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Moderate cytoplasmic staining was observed in few cases of melanomas, endometrial, skin and liver cancers while cases of ovarian and endometrial cancer were strongly stained. Several testicular cancers showed weak to moderate nuclear positivity. Remaining cancers were generally negative.
Several cases of prostate and breast cancers showed moderate cytoplasmic positivity. Remaining cancers were in general weakly stained or negative.
GENE INFORMATION
Gene name
ZSCAN25 (HGNC Symbol)
Synonyms
FLJ32468, ZNF498
Description
Zinc finger and SCAN domain containing 25 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined. [provided by RefSeq, Jul 2008]
