Cell atlas - ZSCAN25 - The Human Protein Atlas

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ZSCAN25

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli fibrillar center
	Nucleus

Human cell
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZSCAN25
Gene description	Zinc finger and SCAN domain containing 25
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli (fibrillar center). In addition localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli fibrillar center (approved)
Additional location	In addition localized to the Nucleus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA055127
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli (fibrillar center). In addition localized to the nucleus.

Main location

Nucleoli fibrillar center (approved)

Additional location

Nucleus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA055127	CACO-2	Nucleus
	HPA055127	CACO-2	Nucleoli fibrillar center
	HPA055127	U-2 OS	Nucleus
	HPA055127	U-2 OS	Nucleoli fibrillar center
	HPA055127	U-251 MG	Nucleus
	HPA055127	U-251 MG	Nucleoli fibrillar center

GENE INFORMATION
Gene name	ZSCAN25 (HGNC Symbol)
Synonyms	FLJ32468, ZNF498
Description	Zinc finger and SCAN domain containing 25 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	99616946 - 99632407
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197037 (version 83.38)
Entrez gene	221785
UniProt	Q6NSZ9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6NSZ9
Antibodypedia	ZSCAN25 antibodies

PROTEIN BROWSER

ZSCAN25-001	ZSCAN25-005	ZSCAN25-201	ZSCAN25-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZSCAN25-001 ENSP00000377708 ENST00000394152	Q6NSZ9 [Direct mapping] Zinc finger and SCAN domain-containing protein 25 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] Show all	544 aa 61.5 kDa	No	0
ZSCAN25-005 ENSP00000413144 ENST00000431485	C9K079 [Direct mapping] Zinc finger and SCAN domain-containing protein 25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	70 aa 8.4 kDa	No	0
ZSCAN25-201 ENSP00000262941 ENST00000262941	A0A0C4DFN0 [Direct mapping] Zinc finger and SCAN domain-containing protein 25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	465 aa 52.9 kDa	No	0
ZSCAN25-202 ENSP00000334800 ENST00000334715	Q6NSZ9 [Direct mapping] Zinc finger and SCAN domain-containing protein 25 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] Show all	544 aa 61.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.