Expression of ZSCAN5B in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger and SCAN domain containing 5B

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA043123	HPA046836	HPA059494

Tissue	Cancer staining	Protein expression of normal tissue
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma

Tissue	Cancer staining	Protein expression of normal tissue
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary	Cases of squamous cell carcinomas, prostate and urothelial cancers showed weak to moderate cytoplasmic staining. Remaining cancers were generally negative.

GENE INFORMATION
Gene name	ZSCAN5B (HGNC Symbol)
Synonyms	ZNF371, ZNF495B
Description	Zinc finger and SCAN domain containing 5B (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.43
Chromosome location (bp)	56189570 - 56197920
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197213 (version 83.38)
Entrez gene	342933
UniProt	A6NJL1 (UniProt - Inferred from homology)
neXtProt	NX_A6NJL1
Antibodypedia	ZSCAN5B antibodies

PROTEIN BROWSER

ZSCAN5B-001	ZSCAN5B-002	ZSCAN5B-003	ZSCAN5B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZSCAN5B-001 ENSP00000466072 ENST00000586855	A6NJL1 [Direct mapping] Zinc finger and SCAN domain-containing protein 5B Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	495 aa 55.8 kDa	No	0
ZSCAN5B-002 ENSP00000465118 ENST00000589938	K7EJD1 [Direct mapping] Zinc finger and SCAN domain-containing protein 5B Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	169 aa 19.3 kDa	No	0
ZSCAN5B-003 ENSP00000468660 ENST00000587032	K7ESD3 [Direct mapping] Zinc finger and SCAN domain-containing protein 5B Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	137 aa 15.8 kDa	No	0
ZSCAN5B-201 ENSP00000351883 ENST00000358992	A6NJL1 [Direct mapping] Zinc finger and SCAN domain-containing protein 5B Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	495 aa 55.8 kDa	No	0