Expression of SLC2A10 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 2 (facilitated glucose transporter), member 10

Protein class

Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041015

GENE INFORMATION
Gene name	SLC2A10 (HGNC Symbol)
Synonyms	GLUT10
Description	Solute carrier family 2 (facilitated glucose transporter), member 10 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.[provided by RefSeq, Dec 2009]
Chromosome	20
Cytoband	q13.12
Chromosome location (bp)	46709487 - 46736347
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197496 (version 83.38)
Entrez gene	81031
UniProt	O95528 (UniProt - Evidence at protein level)
neXtProt	NX_O95528
Antibodypedia	SLC2A10 antibodies

PROTEIN BROWSER

SLC2A10-001	SLC2A10-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC2A10-001 ENSP00000352216 ENST00000359271	O95528 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 10 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0012505 [endomembrane system] GO:0015758 [glucose transport] GO:0015992 [proton transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:0048471 [perinuclear region of cytoplasm] GO:0055085 [transmembrane transport] GO:1904659 [glucose transmembrane transport] Show all	541 aa 56.9 kDa	No	>9
SLC2A10-002 ENSP00000478679 ENST00000486000	A0A087WUH5 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005887 [integral component of plasma membrane] GO:0015992 [proton transport] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:1904659 [glucose transmembrane transport] Show all	13 aa 1.4 kDa	No	0