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SLC2A10

GENERAL INFORMATION

Gene name

 SLC2A10

Gene description

 Solute carrier family 2 (facilitated glucose transporter), member 10

Protein class

 Disease related genes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

 Intracellular,Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and membranous expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA041015
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SLC2A10 (HGNC Symbol)

Synonyms

 GLUT10

Description

 Solute carrier family 2 (facilitated glucose transporter), member 10 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.[provided by RefSeq, Dec 2009]

Chromosome

 20

Cytoband

 q13.12

Chromosome location (bp)

 46709487 - 46736347

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197496 (version 83.38)

Entrez gene

 81031

UniProt

 O95528 (UniProt - Evidence at protein level)

neXtProt

 NX_O95528

Antibodypedia

 SLC2A10 antibodies

PROTEIN BROWSER
SLC2A10-001
SLC2A10-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC2A10-001
ENSP00000352216
ENST00000359271
O95528 [Direct mapping]
Solute carrier family 2, facilitated glucose transporter member 10
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Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005215 [transporter activity]
GO:0005351 [sugar:proton symporter activity]
GO:0005355 [glucose transmembrane transporter activity]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0012505 [endomembrane system]
GO:0015758 [glucose transport]
GO:0015992 [proton transport]
GO:0016021 [integral component of membrane]
GO:0022857 [transmembrane transporter activity]
GO:0035428 [hexose transmembrane transport]
GO:0046323 [glucose import]
GO:0048471 [perinuclear region of cytoplasm]
GO:0055085 [transmembrane transport]
GO:1904659 [glucose transmembrane transport]
Show all
 541 aa
56.9 kDa 		No >9
SLC2A10-002
ENSP00000478679
ENST00000486000
A0A087WUH5 [Direct mapping]
Solute carrier family 2, facilitated glucose transporter member 10
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005351 [sugar:proton symporter activity]
GO:0005355 [glucose transmembrane transporter activity]
GO:0005887 [integral component of plasma membrane]
GO:0015992 [proton transport]
GO:0035428 [hexose transmembrane transport]
GO:0046323 [glucose import]
GO:1904659 [glucose transmembrane transport]
Show all
 13 aa
1.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.