Expression of SLC28A3 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 28 (concentrative nucleoside transporter), member 3

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA023311	HPA024729

GENE INFORMATION
Gene name	SLC28A3 (HGNC Symbol)
Synonyms	CNT3
Description	Solute carrier family 28 (concentrative nucleoside transporter), member 3 (HGNC Symbol)
Entrez gene summary	Nucleoside transporters, such as SLC28A3, regulate multiple cellular processes, including neurotransmission, vascular tone, adenosine concentration in the vicinity of cell surface receptors, and transport and metabolism of nucleoside drugs. SLC28A3 shows broad specificity for pyrimidine and purine nucleosides (Ritzel et al., 2001 [PubMed 11032837]).[supplied by OMIM, Mar 2008]
Chromosome	9
Cytoband
Chromosome location (bp)	84275457 - 84340683
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197506 (version 83.38)
Entrez gene	64078
UniProt	Q9HAS3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HAS3
Antibodypedia	SLC28A3 antibodies

PROTEIN BROWSER

SLC28A3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC28A3-001 ENSP00000365413 ENST00000376238	Q9HAS3 [Direct mapping] Solute carrier family 28 member 3 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0001895 [retina homeostasis] GO:0005415 [nucleoside:sodium symporter activity] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006810 [transport] GO:0006863 [purine nucleobase transport] GO:0015389 [pyrimidine- and adenine-specific:sodium symporter activity] GO:0015390 [purine-specific nucleoside:sodium symporter activity] GO:0015855 [pyrimidine nucleobase transport] GO:0015860 [purine nucleoside transmembrane transport] GO:0015864 [pyrimidine nucleoside transport] GO:0016020 [membrane] GO:0035725 [sodium ion transmembrane transport] GO:0055085 [transmembrane transport] GO:0072531 [pyrimidine-containing compound transmembrane transport] Show all	691 aa 76.9 kDa	No	>9