Cell atlas - LHFPL5 - The Human Protein Atlas

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LHFPL5

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	LHFPL5
Gene description	Lipoma HMGIC fusion partner-like 5
Protein class	Disease related genes Potential drug targets Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	LHFPL5 (HGNC Symbol)
Synonyms	DFNB67, dJ510O8.8, MGC33835, Tmhs
Description	Lipoma HMGIC fusion partner-like 5 (HGNC Symbol)
Entrez gene summary	This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in this gene result in deafness in humans, and a mutation in a similar gene in mice results in deafness and vestibular dysfunction with severe degeneration of the organ of Corti. It is proposed to function in hair bundle morphogenesis. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	p21.31
Chromosome location (bp)	35805293 - 35833874
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197753 (version 83.38)
Entrez gene	222662
UniProt	Q8TAF8 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TAF8
Antibodypedia	LHFPL5 antibodies

PROTEIN BROWSER

LHFPL5-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LHFPL5-002 ENSP00000353346 ENST00000360215	Q8TAF8 [Direct mapping] Tetraspan membrane protein of hair cell stereocilia Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0006811 [ion transport] GO:0007605 [sensory perception of sound] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] GO:0032421 [stereocilium bundle] GO:0032426 [stereocilium bundle tip] GO:0050910 [detection of mechanical stimulus involved in sensory perception of sound] GO:0060088 [auditory receptor cell stereocilium organization] Show all	219 aa 24.2 kDa	No	4

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.