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IFNA1

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GENERAL INFORMATION

Gene name

 IFNA1

Gene description

 Interferon, alpha 1

Protein class

 Cancer-related genes
Plasma proteins
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (HeLa)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HeLa)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 IFNA1 (HGNC Symbol)

Synonyms

 IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@

Description

 Interferon, alpha 1 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011]

Chromosome

 9

Cytoband

 p21.3

Chromosome location (bp)

 21409169 - 21441316

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197919 (version 83.38)

Entrez gene

 3439

UniProt

 P01562 (UniProt - Evidence at protein level)

neXtProt

 NX_P01562

Antibodypedia

 IFNA1 antibodies

PROTEIN BROWSER
IFNA1-001
IFNA1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
IFNA1-001
ENSP00000276927
ENST00000276927
P01562 [Direct mapping]
Interferon alpha-1/13
L0N195 [Target identity:100%; Query identity:100%]
Interferon-alpha1
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Show all
GO:0002250 [adaptive immune response]
GO:0002286 [T cell activation involved in immune response]
GO:0002323 [natural killer cell activation involved in immune response]
GO:0005125 [cytokine activity]
GO:0005126 [cytokine receptor binding]
GO:0005132 [type I interferon receptor binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006959 [humoral immune response]
GO:0007596 [blood coagulation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030183 [B cell differentiation]
GO:0033141 [positive regulation of peptidyl-serine phosphorylation of STAT protein]
GO:0042100 [B cell proliferation]
GO:0043330 [response to exogenous dsRNA]
GO:0045087 [innate immune response]
GO:0051607 [defense response to virus]
GO:0060337 [type I interferon signaling pathway]
GO:0060338 [regulation of type I interferon-mediated signaling pathway]
Show all
 189 aa
21.7 kDa 		Yes 0
IFNA1-201
ENSP00000485003
ENST00000613815
A0A087X2I3 [Direct mapping]
Interferon alpha-1/13
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0002250 [adaptive immune response]
GO:0002286 [T cell activation involved in immune response]
GO:0002323 [natural killer cell activation involved in immune response]
GO:0005125 [cytokine activity]
GO:0005126 [cytokine receptor binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0006952 [defense response]
GO:0006959 [humoral immune response]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030183 [B cell differentiation]
GO:0033141 [positive regulation of peptidyl-serine phosphorylation of STAT protein]
GO:0042100 [B cell proliferation]
GO:0043330 [response to exogenous dsRNA]
GO:0051607 [defense response to virus]
Show all
 189 aa
22.1 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.