Tissue expression of DLGAP2 - Summary - The Human Protein Atlas

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DLGAP2

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	DLGAP2
Gene description	Discs, large (Drosophila) homolog-associated protein 2
Protein class	Nuclear receptors Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (testis, cerebral cortex)
GTEx:	Group enriched (cerebral cortex, testis, caudate, pituitary gland, hippocampus, hypothalamus)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results.
Reliability score	Uncertain based on 1 antibody. HPA030320
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

Skeletal muscle

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (testis, cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (cerebral cortex, testis, caudate, pituitary gland, hippocampus, hypothalamus)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	DLGAP2 (HGNC Symbol)
Synonyms	DAP-2
Description	Discs, large (Drosophila) homolog-associated protein 2 (HGNC Symbol)
Entrez gene summary	The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014]
Chromosome	8
Cytoband	p23.3
Chromosome location (bp)	1501366 - 1708476
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198010 (version 83.38)
Entrez gene	9228
UniProt	Q9P1A6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P1A6
Antibodypedia	DLGAP2 antibodies

PROTEIN BROWSER

DLGAP2-001	DLGAP2-003	DLGAP2-004	DLGAP2-005	DLGAP2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DLGAP2-001 ENSP00000400258 ENST00000421627	Q9P1A6 [Direct mapping] Disks large-associated protein 2 Show all	Nuclear receptors Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005883 [neurofilament] GO:0007270 [neuron-neuron synaptic transmission] GO:0014069 [postsynaptic density] GO:0023052 [signaling] GO:0030054 [cell junction] GO:0045211 [postsynaptic membrane] Show all	975 aa 108.9 kDa	No	0
DLGAP2-003 ENSP00000430563 ENST00000520901	H0YBY6 [Direct mapping] Disks large-associated protein 2 Show all	Predicted intracellular proteins Show all	GO:0007270 [neuron-neuron synaptic transmission] GO:0023052 [signaling] Show all	961 aa 107.2 kDa	No	0
DLGAP2-004 ENSP00000488445 ENST00000518530		Predicted intracellular proteins Show all	GO:0023052 [signaling] Show all	158 aa 18.1 kDa	No	0
DLGAP2-005 ENSP00000488645 ENST00000522499		Predicted intracellular proteins Show all	GO:0023052 [signaling] Show all	176 aa 19.8 kDa	No	0
DLGAP2-201 ENSP00000484215 ENST00000612087	A0A087X1H7 [Direct mapping] Disks large-associated protein 2 Show all	Predicted intracellular proteins Show all	GO:0023052 [signaling] Show all	961 aa 107.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.