Expression of GPN1 in cancer - Summary - The Human Protein Atlas

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GPN1

TISSUE

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CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

GPN-loop GTPase 1

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA036793	HPA036794	CAB037303

GENE INFORMATION
Gene name	GPN1 (HGNC Symbol)
Synonyms	ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1
Description	GPN-loop GTPase 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Chromosome	2
Cytoband	p23.3
Chromosome location (bp)	27628247 - 27651508
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198522 (version 83.38)
Entrez gene	11321
UniProt	Q9HCN4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HCN4
Antibodypedia	GPN1 antibodies

PROTEIN BROWSER

GPN1-001	GPN1-003	GPN1-008	GPN1-009	GPN1-010	GPN1-201	GPN1-202	GPN1-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPN1-001 ENSP00000264718 ENST00000264718	Q9HCN4 [Direct mapping] GPN-loop GTPase 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	388 aa 43.3 kDa	No	0
GPN1-003 ENSP00000384255 ENST00000407583	Q9HCN4 [Direct mapping] GPN-loop GTPase 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	362 aa 41 kDa	No	0
GPN1-008 ENSP00000427269 ENST00000503738	Q9HCN4 [Direct mapping] GPN-loop GTPase 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	279 aa 31.8 kDa	No	0
GPN1-009 ENSP00000424678 ENST00000515877	Q9HCN4 [Direct mapping] GPN-loop GTPase 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	295 aa 33.5 kDa	No	0
GPN1-010 ENSP00000476446 ENST00000610189	Q9HCN4 [Direct mapping] GPN-loop GTPase 1 Q53RZ9 [Target identity:100%; Query identity:100%] Putative uncharacterized protein MBDin; XPA binding protein 1, GTPase, isoform CRA_b; cDNA, FLJ93453, Homo sapiens XPA binding protein 1 (XAB1), mRNA Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	374 aa 41.7 kDa	No	0
GPN1-201 ENSP00000398115 ENST00000424214	Q9HCN4 [Direct mapping] GPN-loop GTPase 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	295 aa 33.5 kDa	No	0
GPN1-202 ENSP00000412170 ENST00000458167	Q9HCN4 [Direct mapping] GPN-loop GTPase 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	279 aa 31.8 kDa	No	0
GPN1-203 ENSP00000484680 ENST00000616939	Q9HCN4 [Direct mapping] GPN-loop GTPase 1 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	388 aa 43.3 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.