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Most cancer tissues showed weak to moderate nuclear and/or cytoplasmic positivity with dot-like pattern in a few cases. Lymphomas, carcinoids, several gliomas and stomach cancers were negative.
GENE INFORMATION
Gene name
TUSC1 (HGNC Symbol)
Synonyms
TSG-9
Description
Tumor suppressor candidate 1 (HGNC Symbol)
Entrez gene summary
This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis. [provided by RefSeq, Jul 2008]
