Expression of LIME1 in cancer - Summary - The Human Protein Atlas

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LIME1

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Lck interacting transmembrane adaptor 1

Protein class

Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

CAB015363

GENE INFORMATION
Gene name	LIME1 (HGNC Symbol)
Synonyms	dJ583P15.4, FLJ20406, LIME
Description	Lck interacting transmembrane adaptor 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a transmembrane adaptor protein that links the T and B-cell receptor stimulation to downstream signaling pathways via its association with the Src family kinases Lck and Lyn, respectively. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015]
Chromosome	20
Cytoband	q13.33
Chromosome location (bp)	63736283 - 63739103
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000203896 (version 83.38)
Entrez gene	54923
UniProt	Q9H400 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H400
Antibodypedia	LIME1 antibodies

PROTEIN BROWSER

LIME1-001	LIME1-002	LIME1-004	LIME1-006	LIME1-008	LIME1-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LIME1-001 ENSP00000477561 ENST00000480139	A0A087WT39 [Direct mapping] Lck-interacting transmembrane adapter 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0050852 [T cell receptor signaling pathway] GO:0050853 [B cell receptor signaling pathway] Show all	176 aa 18.1 kDa	Yes	0
LIME1-002 ENSP00000476772 ENST00000493265	V9GYI1 [Direct mapping] Lck-interacting transmembrane adapter 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0050852 [T cell receptor signaling pathway] GO:0050853 [B cell receptor signaling pathway] Show all	131 aa 13.5 kDa	Yes	0
LIME1-004 ENSP00000478705 ENST00000476183	A0A087WUJ1 [Direct mapping] Lck-interacting transmembrane adapter 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0050852 [T cell receptor signaling pathway] GO:0050853 [B cell receptor signaling pathway] Show all	253 aa 27.2 kDa	Yes	0
LIME1-006 ENSP00000309521 ENST00000309546	Q9H400 [Direct mapping] Lck-interacting transmembrane adapter 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002250 [adaptive immune response] GO:0005615 [extracellular space] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050852 [T cell receptor signaling pathway] GO:0050853 [B cell receptor signaling pathway] Show all	295 aa 31.3 kDa	Yes	0
LIME1-008 ENSP00000414506 ENST00000444951	X6RKG5 [Direct mapping] Lck-interacting transmembrane adapter 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0050852 [T cell receptor signaling pathway] GO:0050853 [B cell receptor signaling pathway] Show all	107 aa 11.9 kDa	Yes	0
LIME1-011 ENSP00000482812 ENST00000487026	A0A087WZP9 [Direct mapping] Lck-interacting transmembrane adapter 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0050852 [T cell receptor signaling pathway] GO:0050853 [B cell receptor signaling pathway] Show all	211 aa 21.7 kDa	Yes	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.