Expression of SYT15 in cancer - Summary

CANCER ATLAS

Gene description

Synaptotagmin XV

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Skin cancer

STAINING SUMMARY

HPA036971	HPA036972

GENE INFORMATION
Gene name	SYT15 (HGNC Symbol)
Synonyms	CHR10SYT
Description	Synaptotagmin XV (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the Synaptotagmin (Syt) family of membrane trafficking proteins. Members of this family contain a transmembrane region and a C-terminal-type tandem C2 domain. Unlike related family members, the encoded protein may be involved in membrane trafficking in non-neuronal tissues. Two trancript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q11.22
Chromosome location (bp)	46578217 - 46594173
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000204176 (version 83.38)
Entrez gene	83849
UniProt	Q9BQS2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BQS2
Antibodypedia	SYT15 antibodies

PROTEIN BROWSER

SYT15-001	SYT15-002	SYT15-003	SYT15-004	SYT15-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SYT15-001 ENSP00000363448 ENST00000374328	H3BLX3 [Direct mapping] Synaptotagmin-15 Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005886 [plasma membrane] GO:0016079 [synaptic vesicle exocytosis] GO:0017158 [regulation of calcium ion-dependent exocytosis] GO:0019905 [syntaxin binding] GO:0030276 [clathrin binding] GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter] Show all	180 aa 20.5 kDa	No	0
SYT15-002 ENSP00000363443 ENST00000374323	X6R8R1 [Direct mapping] Synaptotagmin-15 Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005886 [plasma membrane] GO:0016079 [synaptic vesicle exocytosis] GO:0017158 [regulation of calcium ion-dependent exocytosis] GO:0019905 [syntaxin binding] GO:0030276 [clathrin binding] GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter] Show all	474 aa 52.2 kDa	No	0
SYT15-003 ENSP00000427607 ENST00000503753	Q9BQS2 [Direct mapping] Synaptotagmin-15 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0016079 [synaptic vesicle exocytosis] GO:0017158 [regulation of calcium ion-dependent exocytosis] GO:0019905 [syntaxin binding] GO:0030276 [clathrin binding] GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter] Show all	390 aa 43.5 kDa	No	1
SYT15-004 ENSP00000363441 ENST00000374321	Q9BQS2 [Direct mapping] Synaptotagmin-15 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0016079 [synaptic vesicle exocytosis] GO:0017158 [regulation of calcium ion-dependent exocytosis] GO:0019905 [syntaxin binding] GO:0030276 [clathrin binding] GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter] Show all	421 aa 47.4 kDa	No	0
SYT15-005 ENSP00000424803 ENST00000512997	D6RF99 [Direct mapping] Synaptotagmin-15 Show all	Predicted intracellular proteins Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005886 [plasma membrane] GO:0016079 [synaptic vesicle exocytosis] GO:0017158 [regulation of calcium ion-dependent exocytosis] GO:0019905 [syntaxin binding] GO:0030276 [clathrin binding] GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter] Show all	136 aa 15.8 kDa	No	0