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SYT15

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GENERAL INFORMATION

Gene name

 SYT15

Gene description

 Synaptotagmin XV

Protein class

 Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the Golgi apparatus. Caution: Based on antibodies targeting proteins from multiple genes.

RNA cell category

 Cell line enhanced (SK-BR-3)

Protein evidence

 Evidence at transcript level

Main location

 Localized to the Golgi apparatus (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA064559
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SK-BR-3)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the Golgi apparatus. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

 Golgi apparatus (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA064559 A549 Golgi apparatus
HPA064559 HaCaT Golgi apparatus
HPA064559 U-2 OS Golgi apparatus

GENE INFORMATION

Gene name

 SYT15 (HGNC Symbol)

Synonyms

 CHR10SYT

Description

 Synaptotagmin XV (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the Synaptotagmin (Syt) family of membrane trafficking proteins. Members of this family contain a transmembrane region and a C-terminal-type tandem C2 domain. Unlike related family members, the encoded protein may be involved in membrane trafficking in non-neuronal tissues. Two trancript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 10

Cytoband

 q11.22

Chromosome location (bp)

 46578217 - 46594173

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000204176 (version 83.38)

Entrez gene

 83849

UniProt

 Q9BQS2 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9BQS2

Antibodypedia

 SYT15 antibodies

PROTEIN BROWSER
SYT15-001
SYT15-002
SYT15-003
SYT15-004
SYT15-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SYT15-001
ENSP00000363448
ENST00000374328
H3BLX3 [Direct mapping]
Synaptotagmin-15
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Predicted intracellular proteins
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005886 [plasma membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0017158 [regulation of calcium ion-dependent exocytosis]
GO:0019905 [syntaxin binding]
GO:0030276 [clathrin binding]
GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter]
Show all
 180 aa
20.5 kDa 		No 0
SYT15-002
ENSP00000363443
ENST00000374323
X6R8R1 [Direct mapping]
Synaptotagmin-15
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Predicted intracellular proteins
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005886 [plasma membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0017158 [regulation of calcium ion-dependent exocytosis]
GO:0019905 [syntaxin binding]
GO:0030276 [clathrin binding]
GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter]
Show all
 474 aa
52.2 kDa 		No 0
SYT15-003
ENSP00000427607
ENST00000503753
Q9BQS2 [Direct mapping]
Synaptotagmin-15
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005886 [plasma membrane]
GO:0016021 [integral component of membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0017158 [regulation of calcium ion-dependent exocytosis]
GO:0019905 [syntaxin binding]
GO:0030276 [clathrin binding]
GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter]
Show all
 390 aa
43.5 kDa 		No 1
SYT15-004
ENSP00000363441
ENST00000374321
Q9BQS2 [Direct mapping]
Synaptotagmin-15
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005886 [plasma membrane]
GO:0016021 [integral component of membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0017158 [regulation of calcium ion-dependent exocytosis]
GO:0019905 [syntaxin binding]
GO:0030276 [clathrin binding]
GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter]
Show all
 421 aa
47.4 kDa 		No 0
SYT15-005
ENSP00000424803
ENST00000512997
D6RF99 [Direct mapping]
Synaptotagmin-15
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Predicted intracellular proteins
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005886 [plasma membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0017158 [regulation of calcium ion-dependent exocytosis]
GO:0019905 [syntaxin binding]
GO:0030276 [clathrin binding]
GO:0048791 [calcium ion-dependent exocytosis of neurotransmitter]
Show all
 136 aa
15.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.