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GNL1

GENERAL INFORMATION

Gene name

 GNL1

Gene description

 Guanine nucleotide binding protein-like 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Mainly cytoplasmic expression in all tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 2 antibodies.
HPA043338 , CAB033575
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GNL1 (HGNC Symbol)

Synonyms

 HSR1

Description

 Guanine nucleotide binding protein-like 1 (HGNC Symbol)

Entrez gene summary

 The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008]

Chromosome

 6

Cytoband

 p21.33

Chromosome location (bp)

 30541377 - 30557174

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000204590 (version 83.38)

Entrez gene

 2794

UniProt

 P36915 (UniProt - Evidence at protein level)

neXtProt

 NX_P36915

Antibodypedia

 GNL1 antibodies

PROTEIN BROWSER
GNL1-001
GNL1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GNL1-001
ENSP00000365806
ENST00000376621
P36915 [Direct mapping]
Guanine nucleotide-binding protein-like 1
A0A024RCR2 [Target identity:100%; Query identity:100%]
Guanine nucleotide binding protein-like 1, isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0002456 [T cell mediated immunity]
GO:0003924 [GTPase activity]
GO:0005198 [structural molecule activity]
GO:0005525 [GTP binding]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0007165 [signal transduction]
GO:0042254 [ribosome biogenesis]
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 607 aa
68.7 kDa 		No 0
GNL1-002
ENSP00000404728
ENST00000433809
A2AB27 [Direct mapping]
Guanine nucleotide-binding protein-like 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0042254 [ribosome biogenesis]
Show all
 264 aa
31 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.