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TRIM40

CANCER ATLAS

Gene description

 Tripartite motif containing 40

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA043818

GENE INFORMATION

Gene name

 TRIM40 (HGNC Symbol)

Synonyms

 RNF35

Description

 Tripartite motif containing 40 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the tripartite motif (TRIM) protein family. The encoded protein may play a role as a negative regulator against inflammation and carcinogenesis in the gastrointestinal tract. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014]

Chromosome

 6

Cytoband

 p22.1

Chromosome location (bp)

 30136108 - 30148735

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000204614 (version 83.38)

Entrez gene

 135644

UniProt

 Q6P9F5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6P9F5

Antibodypedia

 TRIM40 antibodies

PROTEIN BROWSER
TRIM40-001
TRIM40-002
TRIM40-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRIM40-001
ENSP00000379826
ENST00000396581
Q6P9F5 [Direct mapping]
Tripartite motif-containing protein 40
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0008270 [zinc ion binding]
GO:0008385 [IkappaB kinase complex]
GO:0030308 [negative regulation of cell growth]
GO:0032088 [negative regulation of NF-kappaB transcription factor activity]
GO:0042177 [negative regulation of protein catabolic process]
GO:0045116 [protein neddylation]
GO:1900181 [negative regulation of protein localization to nucleus]
GO:1901223 [negative regulation of NIK/NF-kappaB signaling]
Show all
 258 aa
29.3 kDa 		No 0
TRIM40-002
ENSP00000308310
ENST00000307859
Q6P9F5 [Direct mapping]
Tripartite motif-containing protein 40
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0008270 [zinc ion binding]
GO:0008385 [IkappaB kinase complex]
GO:0032088 [negative regulation of NF-kappaB transcription factor activity]
GO:0042177 [negative regulation of protein catabolic process]
GO:0045116 [protein neddylation]
GO:1900181 [negative regulation of protein localization to nucleus]
GO:1901223 [negative regulation of NIK/NF-kappaB signaling]
Show all
 229 aa
26.1 kDa 		No 0
TRIM40-202
ENSP00000365914
ENST00000376724
Q6P9F5 [Direct mapping]
Tripartite motif-containing protein 40
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0008270 [zinc ion binding]
GO:0008385 [IkappaB kinase complex]
GO:0032088 [negative regulation of NF-kappaB transcription factor activity]
GO:0042177 [negative regulation of protein catabolic process]
GO:0045116 [protein neddylation]
GO:1900181 [negative regulation of protein localization to nucleus]
GO:1901223 [negative regulation of NIK/NF-kappaB signaling]
Show all
 258 aa
29.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.