Expression of ZFP57 in cancer - Summary

CANCER ATLAS

Gene description

ZFP57 zinc finger protein

Protein class

Disease related genes, Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA047172

GENE INFORMATION
Gene name	ZFP57 (HGNC Symbol)
Synonyms	bA145L22, bA145L22.2, C6orf40, ZNF698
Description	ZFP57 zinc finger protein (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).[provided by RefSeq, Sep 2009]
Chromosome	6
Cytoband	p22.1
Chromosome location (bp)	29672392 - 29681110
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204644 (version 83.38)
Entrez gene	346171
UniProt	Q9NU63 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NU63
Antibodypedia	ZFP57 antibodies

PROTEIN BROWSER

ZFP57-001	ZFP57-002	ZFP57-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZFP57-001 ENSP00000366080 ENST00000376883	Q9NU63 [Direct mapping] Zinc finger protein 57 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006349 [regulation of gene expression by genetic imprinting] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043045 [DNA methylation involved in embryo development] GO:0046872 [metal ion binding] Show all	516 aa 59.2 kDa	No	0
ZFP57-002 ENSP00000418259 ENST00000488757	Q9NU63 [Direct mapping] Zinc finger protein 57 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005720 [nuclear heterochromatin] GO:0006349 [regulation of gene expression by genetic imprinting] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043045 [DNA methylation involved in embryo development] GO:0046872 [metal ion binding] Show all	536 aa 61.4 kDa	No	0
ZFP57-201 ENSP00000366078 ENST00000376881	Q9NU63 [Direct mapping] Zinc finger protein 57 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006349 [regulation of gene expression by genetic imprinting] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0043045 [DNA methylation involved in embryo development] GO:0046872 [metal ion binding] Show all	452 aa 51.9 kDa	No	0