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ZFP57

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GENERAL INFORMATION

Gene name

 ZFP57

Gene description

 ZFP57 zinc finger protein

Protein class

 Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enriched (BEWO)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (BEWO)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 ZFP57 (HGNC Symbol)

Synonyms

 bA145L22, bA145L22.2, C6orf40, ZNF698

Description

 ZFP57 zinc finger protein (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).[provided by RefSeq, Sep 2009]

Chromosome

 6

Cytoband

 p22.1

Chromosome location (bp)

 29672392 - 29681110

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000204644 (version 83.38)

Entrez gene

 346171

UniProt

 Q9NU63 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NU63

Antibodypedia

 ZFP57 antibodies

PROTEIN BROWSER
ZFP57-001
ZFP57-002
ZFP57-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZFP57-001
ENSP00000366080
ENST00000376883
Q9NU63 [Direct mapping]
Zinc finger protein 57 homolog
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Disease related genes
Show all
GO:0003676 [nucleic acid binding]
GO:0005622 [intracellular]
GO:0006349 [regulation of gene expression by genetic imprinting]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043045 [DNA methylation involved in embryo development]
GO:0046872 [metal ion binding]
Show all
 516 aa
59.2 kDa 		No 0
ZFP57-002
ENSP00000418259
ENST00000488757
Q9NU63 [Direct mapping]
Zinc finger protein 57 homolog
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005720 [nuclear heterochromatin]
GO:0006349 [regulation of gene expression by genetic imprinting]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043045 [DNA methylation involved in embryo development]
GO:0046872 [metal ion binding]
Show all
 536 aa
61.4 kDa 		No 0
ZFP57-201
ENSP00000366078
ENST00000376881
Q9NU63 [Direct mapping]
Zinc finger protein 57 homolog
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Disease related genes
Show all
GO:0003676 [nucleic acid binding]
GO:0005622 [intracellular]
GO:0006349 [regulation of gene expression by genetic imprinting]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043045 [DNA methylation involved in embryo development]
GO:0046872 [metal ion binding]
Show all
 452 aa
51.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.