Tissue expression of CRYZL1 - Summary - The Human Protein Atlas

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CRYZL1

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CRYZL1
Gene description	Crystallin, zeta (quinone reductase)-like 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	14
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 3 antibodies. HPA019120 , HPA029399 , CAB034129
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	CRYZL1 (HGNC Symbol)
Synonyms	4P11, QOH-1
Description	Crystallin, zeta (quinone reductase)-like 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]
Chromosome	21
Cytoband	q22.11
Chromosome location (bp)	33589341 - 33643926
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000205758 (version 83.38)
Entrez gene	9946
UniProt	O95825 (UniProt - Evidence at protein level)
neXtProt	NX_O95825
Antibodypedia	CRYZL1 antibodies

PROTEIN BROWSER

CRYZL1-001	CRYZL1-002	CRYZL1-003	CRYZL1-004	CRYZL1-007	CRYZL1-008	CRYZL1-011	CRYZL1-012	CRYZL1-013	CRYZL1-014	CRYZL1-017	CRYZL1-018	CRYZL1-021	CRYZL1-024

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CRYZL1-001 ENSP00000370966 ENST00000381554	O95825 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003960 [NADPH:quinone reductase activity] GO:0005829 [cytosol] GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0050661 [NADP binding] GO:0055114 [oxidation-reduction process] GO:1901661 [quinone metabolic process] Show all	349 aa 38.7 kDa	No	0
CRYZL1-002 ENSP00000370951 ENST00000381540	A6NND8 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	322 aa 35.5 kDa	No	0
CRYZL1-003 ENSP00000355075 ENST00000361534	A6NHJ8 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	325 aa 36.1 kDa	No	0
CRYZL1-004 ENSP00000382371 ENST00000399442	A8MZ10 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		24 aa 3 kDa	No	0
CRYZL1-007 ENSP00000290244 ENST00000290244	A6NMA8 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	334 aa 37.1 kDa	No	0
CRYZL1-008 ENSP00000389209 ENST00000413017	A0A0C4DG14 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	113 aa 12.4 kDa	No	0
CRYZL1-011 ENSP00000408385 ENST00000438788	C9JNR9 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		19 aa 2.3 kDa	No	0
CRYZL1-012 ENSP00000387660 ENST00000426935	C9K0F7 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	158 aa 17.2 kDa	No	0
CRYZL1-013 ENSP00000405510 ENST00000431177	C9JAL0 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	181 aa 19.9 kDa	No	0
CRYZL1-014 ENSP00000402844 ENST00000417979	C9JQD0 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	107 aa 11.7 kDa	No	0
CRYZL1-017 ENSP00000412087 ENST00000440526	H7C3I5 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	241 aa 26.2 kDa	No	0
CRYZL1-018 ENSP00000409387 ENST00000414079	H7C338 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	97 aa 10.3 kDa	No	0
CRYZL1-021 ENSP00000397318 ENST00000441940	H7C0X3 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	111 aa 12.5 kDa	No	0
CRYZL1-024 ENSP00000399730 ENST00000445393	C9JZK8 [Direct mapping] Quinone oxidoreductase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008270 [zinc ion binding] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	197 aa 22.4 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
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