Expression of RBMXL1 in cancer - Summary

CANCER ATLAS

Gene description

RNA binding motif protein, X-linked-like 1

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA057707

GENE INFORMATION
Gene name	RBMXL1 (HGNC Symbol)
Synonyms	KAT3
Description	RNA binding motif protein, X-linked-like 1 (HGNC Symbol)
Entrez gene summary	This gene represents a retrogene of RNA binding motif protein, X-linked (RBMX), which is located on chromosome X. While all introns in the coding sequence have been processed out compared to the RBMX locus, the ORF is intact and there is specific evidence for transcription at this location. The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional, possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis. This gene shares 5' exon structure with the cysteine conjugate-beta lyase 2 locus on chromosome 1, but the coding sequences are non-overlapping. Alternative splicing results in two transcript variants. [provided by RefSeq, Jun 2009]
Chromosome	1
Cytoband	p22.2
Chromosome location (bp)	88979456 - 88992960
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000213516 (version 83.38)
Entrez gene	494115
UniProt	Q96E39 (UniProt - Evidence at protein level)
neXtProt	NX_Q96E39
Antibodypedia	RBMXL1 antibodies

PROTEIN BROWSER

RBMXL1-001	RBMXL1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBMXL1-001 ENSP00000318415 ENST00000321792	Q96E39 [Direct mapping] RNA binding motif protein, X-linked-like-1 RNA binding motif protein, X-linked-like-1, N-terminally processed Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0030529 [ribonucleoprotein complex] Show all	390 aa 42.1 kDa	No	0
RBMXL1-201 ENSP00000446099 ENST00000399794	Q96E39 [Direct mapping] RNA binding motif protein, X-linked-like-1 RNA binding motif protein, X-linked-like-1, N-terminally processed Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005634 [nucleus] GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0030529 [ribonucleoprotein complex] Show all	390 aa 42.1 kDa	No	0