Tissue expression of LTB4R2 - Summary - The Human Protein Atlas

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LTB4R2

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	LTB4R2
Gene description	Leukotriene B4 receptor 2
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (skin)
FANTOM5:	Tissue enhanced (esophagus, tonsil)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA029680 , CAB022689
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (skin)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (esophagus, tonsil)

GENE INFORMATION
Gene name	LTB4R2 (HGNC Symbol)
Synonyms	BLT2, BLTR2, JULF2, NOP9
Description	Leukotriene B4 receptor 2 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q12
Chromosome location (bp)	24305734 - 24312053
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000213906 (version 83.38)
Entrez gene	56413
UniProt	Q9NPC1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NPC1
Antibodypedia	LTB4R2 antibodies

PROTEIN BROWSER

LTB4R2-001	LTB4R2-002	LTB4R2-003	LTB4R2-004	LTB4R2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LTB4R2-001 ENSP00000432146 ENST00000528054	Q9NPC1 [Direct mapping] Leukotriene B4 receptor 2 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Adenosine and adenine nucleotide receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0001632 [leukotriene B4 receptor activity] GO:0004930 [G-protein coupled receptor activity] GO:0004974 [leukotriene receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007218 [neuropeptide signaling pathway] GO:0008528 [G-protein coupled peptide receptor activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0061737 [leukotriene signaling pathway] Show all	389 aa 41.5 kDa	No	7
LTB4R2-002 ENSP00000433290 ENST00000533293	Q9NPC1 [Direct mapping] Leukotriene B4 receptor 2 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Adenosine and adenine nucleotide receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0001632 [leukotriene B4 receptor activity] GO:0004930 [G-protein coupled receptor activity] GO:0004974 [leukotriene receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007218 [neuropeptide signaling pathway] GO:0008528 [G-protein coupled peptide receptor activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0061737 [leukotriene signaling pathway] Show all	358 aa 37.9 kDa	No	7
LTB4R2-003 ENSP00000434760 ENST00000530080	E9PNJ6 [Direct mapping] Leukotriene B4 receptor 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004974 [leukotriene receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0061737 [leukotriene signaling pathway] Show all	319 aa 33.8 kDa	No	7
LTB4R2-004 ENSP00000436668 ENST00000527924	E9PIC1 [Direct mapping] Leukotriene B4 receptor 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004974 [leukotriene receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0061737 [leukotriene signaling pathway] Show all	160 aa 17.2 kDa	No	4
LTB4R2-201 ENSP00000445772 ENST00000543919	Q9NPC1 [Direct mapping] Leukotriene B4 receptor 2 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Adenosine and adenine nucleotide receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0001632 [leukotriene B4 receptor activity] GO:0004930 [G-protein coupled receptor activity] GO:0004974 [leukotriene receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007218 [neuropeptide signaling pathway] GO:0008528 [G-protein coupled peptide receptor activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0051546 [keratinocyte migration] GO:0061737 [leukotriene signaling pathway] Show all	358 aa 37.9 kDa	No	7

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.