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HAUS3

CANCER ATLAS

Gene description

 HAUS augmin-like complex, subunit 3

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA048190

GENE INFORMATION

Gene name

 HAUS3 (HGNC Symbol)

Synonyms

 C4orf15, dgt3, IT1, MGC4701

Description

 HAUS augmin-like complex, subunit 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a component of the HAUS augmin-like protein complex, which plays a key role in cytokinesis and mitosis. Disruption of the encoded protein causes mitotic defects resulting from fragmentation of centrosomes and microtubule destabilization. This gene shares its 5' exons with some transcripts from overlapping GeneID: 353497, which encodes a DNA polymerase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Chromosome

 4

Cytoband

 p16.3

Chromosome location (bp)

 2227464 - 2242164

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000214367 (version 83.38)

Entrez gene

 79441

UniProt

 Q68CZ6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q68CZ6

Antibodypedia

 HAUS3 antibodies

PROTEIN BROWSER
HAUS3-001
HAUS3-002
HAUS3-003
HAUS3-004
HAUS3-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HAUS3-001
ENSP00000243706
ENST00000243706
Q68CZ6 [Direct mapping]
HAUS augmin-like complex subunit 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
 603 aa
69.6 kDa 		No 0
HAUS3-002
ENSP00000392903
ENST00000443786
Q68CZ6 [Direct mapping]
HAUS augmin-like complex subunit 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
 603 aa
69.6 kDa 		No 0
HAUS3-003
ENSP00000427350
ENST00000506763
Q68CZ6 [Direct mapping]
HAUS augmin-like complex subunit 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0007067 [mitotic nuclear division]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
Show all
 489 aa
56.4 kDa 		No 0
HAUS3-004
ENSP00000427356
ENST00000502440
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 10 aa
1.1 kDa 		No 0
HAUS3-005
ENSP00000423285
ENST00000514395
D6R993 [Direct mapping]
HAUS augmin-like complex subunit 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0051225 [spindle assembly]
GO:0070652 [HAUS complex]
Show all
 33 aa
3.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.