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TRIM26

CANCER ATLAS

Gene description

 Tripartite motif containing 26

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA044975
HPA050456

GENE INFORMATION

Gene name

 TRIM26 (HGNC Symbol)

Synonyms

 RNF95, ZNF173

Description

 Tripartite motif containing 26 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]

Chromosome

 6

Cytoband

 p22.1

Chromosome location (bp)

 30184455 - 30213427

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000234127 (version 83.38)

Entrez gene

 7726

UniProt

 Q12899 (UniProt - Evidence at protein level)

neXtProt

 NX_Q12899

Antibodypedia

 TRIM26 antibodies

PROTEIN BROWSER
TRIM26-001
TRIM26-002
TRIM26-003
TRIM26-005
TRIM26-006
TRIM26-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRIM26-001
ENSP00000391879
ENST00000453195
Q12899 [Direct mapping]
Tripartite motif-containing protein 26
A0A024RCP3 [Target identity:100%; Query identity:100%]
Tripartite motif-containing 26, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0045087 [innate immune response]
GO:0046597 [negative regulation of viral entry into host cell]
GO:0046872 [metal ion binding]
GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:1902187 [negative regulation of viral release from host cell]
Show all
 539 aa
62.2 kDa 		No 0
TRIM26-002
ENSP00000410446
ENST00000454678
Q12899 [Direct mapping]
Tripartite motif-containing protein 26
A0A024RCP3 [Target identity:100%; Query identity:100%]
Tripartite motif-containing 26, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0045087 [innate immune response]
GO:0046597 [negative regulation of viral entry into host cell]
GO:0046872 [metal ion binding]
GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:1902187 [negative regulation of viral release from host cell]
Show all
 539 aa
62.2 kDa 		No 0
TRIM26-003
ENSP00000395491
ENST00000437089
Q12899 [Direct mapping]
Tripartite motif-containing protein 26
A0A024RCP3 [Target identity:100%; Query identity:100%]
Tripartite motif-containing 26, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0045087 [innate immune response]
GO:0046597 [negative regulation of viral entry into host cell]
GO:0046872 [metal ion binding]
GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:1902187 [negative regulation of viral release from host cell]
Show all
 539 aa
62.2 kDa 		No 0
TRIM26-005
ENSP00000413673
ENST00000416596
A2AE48 [Direct mapping]
Tripartite motif-containing protein 26
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0008270 [zinc ion binding]
Show all
 248 aa
28.7 kDa 		No 0
TRIM26-006
ENSP00000387530
ENST00000418026
Q5SPU2 [Direct mapping]
Tripartite motif-containing protein 26
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0008270 [zinc ion binding]
Show all
 157 aa
18.2 kDa 		No 0
TRIM26-008
ENSP00000400920
ENST00000434785
A2AE50 [Direct mapping]
Tripartite motif-containing protein 26
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0008270 [zinc ion binding]
Show all
 122 aa
14 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.