Tissue expression of TRIM26 - Summary - The Human Protein Atlas

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TRIM26

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TRIM26
Gene description	Tripartite motif containing 26
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA044975 , HPA050456
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	TRIM26 (HGNC Symbol)
Synonyms	RNF95, ZNF173
Description	Tripartite motif containing 26 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]
Chromosome	6
Cytoband	p22.1
Chromosome location (bp)	30184455 - 30213427
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000234127 (version 83.38)
Entrez gene	7726
UniProt	Q12899 (UniProt - Evidence at protein level)
neXtProt	NX_Q12899
Antibodypedia	TRIM26 antibodies

PROTEIN BROWSER

TRIM26-001	TRIM26-002	TRIM26-003	TRIM26-005	TRIM26-006	TRIM26-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRIM26-001 ENSP00000391879 ENST00000453195	Q12899 [Direct mapping] Tripartite motif-containing protein 26 A0A024RCP3 [Target identity:100%; Query identity:100%] Tripartite motif-containing 26, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0008270 [zinc ion binding] GO:0019221 [cytokine-mediated signaling pathway] GO:0045087 [innate immune response] GO:0046597 [negative regulation of viral entry into host cell] GO:0046872 [metal ion binding] GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity] GO:0060333 [interferon-gamma-mediated signaling pathway] GO:1902187 [negative regulation of viral release from host cell] Show all	539 aa 62.2 kDa	No	0
TRIM26-002 ENSP00000410446 ENST00000454678	Q12899 [Direct mapping] Tripartite motif-containing protein 26 A0A024RCP3 [Target identity:100%; Query identity:100%] Tripartite motif-containing 26, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0008270 [zinc ion binding] GO:0019221 [cytokine-mediated signaling pathway] GO:0045087 [innate immune response] GO:0046597 [negative regulation of viral entry into host cell] GO:0046872 [metal ion binding] GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity] GO:0060333 [interferon-gamma-mediated signaling pathway] GO:1902187 [negative regulation of viral release from host cell] Show all	539 aa 62.2 kDa	No	0
TRIM26-003 ENSP00000395491 ENST00000437089	Q12899 [Direct mapping] Tripartite motif-containing protein 26 A0A024RCP3 [Target identity:100%; Query identity:100%] Tripartite motif-containing 26, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0008270 [zinc ion binding] GO:0019221 [cytokine-mediated signaling pathway] GO:0045087 [innate immune response] GO:0046597 [negative regulation of viral entry into host cell] GO:0046872 [metal ion binding] GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity] GO:0060333 [interferon-gamma-mediated signaling pathway] GO:1902187 [negative regulation of viral release from host cell] Show all	539 aa 62.2 kDa	No	0
TRIM26-005 ENSP00000413673 ENST00000416596	A2AE48 [Direct mapping] Tripartite motif-containing protein 26 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	248 aa 28.7 kDa	No	0
TRIM26-006 ENSP00000387530 ENST00000418026	Q5SPU2 [Direct mapping] Tripartite motif-containing protein 26 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	157 aa 18.2 kDa	No	0
TRIM26-008 ENSP00000400920 ENST00000434785	A2AE50 [Direct mapping] Tripartite motif-containing protein 26 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	122 aa 14 kDa	No	0

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