Cell atlas - RPP21 - The Human Protein Atlas

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RPP21

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	RPP21
Gene description	Ribonuclease P/MRP 21kDa subunit
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SCLC-21H)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	RPP21 (HGNC Symbol)
Synonyms	C6orf135, Em:AB014085.3, FLJ22638
Description	Ribonuclease P/MRP 21kDa subunit (HGNC Symbol)
Entrez gene summary	RPP21 is a protein subunit of nuclear ribonuclease P, which processes the 5-prime leader sequence of precursor tRNAs (Jarrous et al., 2001 [PubMed 11497433]).[supplied by OMIM, Jan 2009]
Chromosome	6
Cytoband	p22.1
Chromosome location (bp)	30345131 - 30346884
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000241370 (version 83.38)
Entrez gene	79897
UniProt	Q9H633 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H633
Antibodypedia	RPP21 antibodies

PROTEIN BROWSER

RPP21-001	RPP21-002	RPP21-003	RPP21-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPP21-001 ENSP00000403833 ENST00000442966	Q9H633 [Direct mapping] Ribonuclease P protein subunit p21 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0042493 [response to drug] GO:0046872 [metal ion binding] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	154 aa 17.6 kDa	No	0
RPP21-002 ENSP00000397778 ENST00000436442	Q9H633 [Direct mapping] Ribonuclease P protein subunit p21 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0042493 [response to drug] GO:0046872 [metal ion binding] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	144 aa 16.5 kDa	No	0
RPP21-003 ENSP00000394320 ENST00000428040	Q9H633 [Direct mapping] Ribonuclease P protein subunit p21 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0042493 [response to drug] GO:0046872 [metal ion binding] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	177 aa 20 kDa	No	0
RPP21-006 ENSP00000409799 ENST00000433076	Q9H633 [Direct mapping] Ribonuclease P protein subunit p21 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0042493 [response to drug] GO:0046872 [metal ion binding] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	162 aa 18.4 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.